What is ISOLDE?

ISOLDE is a modern, immersive environment designed to ease the historically challenging task of building high-quality macromolecular models into low to medium resolution experimental maps. Read more...

What can it do?

Ease the task of model building at low resolution. Read more...

What can't it do (yet)?

Build your model for you. Read more...

What do I need to run it?

Ideally, a single modern workstation with the best GPU you can afford. However, ISOLDE is still usable even on a MacBook Air. Read more...

How do I get it?

ISOLDE is distributed as a plugin to UCSF ChimeraX, and can be installed via its built-in Tool Shed. Read more...

How do I use it?

ISOLDE comes bundled with comprehensive documentation of its GUI and (for the adventurous) its Python API. This is also provided here.

ISOLDE is developed and maintained by Tristan Croll in the lab of Randy Read at the Cambridge Institute for Medical Research and supported by Prof. Read's Wellcome Trust Principal Research Fellowship 209407/Z/17/Z. Development and testing has been aided by the generous donation of a GTX Titan Xp GPU by NVIDIA Corporation.

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